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Restylane® Silk

Restylane® Silk is an FDA-approved cosmetic dermal filler specially used in the lips and around the mouth. It is composed of hyaluronic acid—a naturally occurring substance in your body that helps to provide fullness and elasticity. Over time, skin loses natural hyaluronic acid, but injections of dermal fillers like Restylane® Silk are able to help fill the wrinkles, lines, and folds caused by this. Restylane® Silk is a smooth gel designed to restore natural youthful definition and symmetry to the lip and mouth area. The benefit of Restylane® Silk is that its smooth consistency allows it to fill in smaller lines and wrinkles without adding bulkiness.

Photo Gallery

  • Photo of a 32-year-old patient treated with2 mL of Restylane Silk in the lips and perioral lines and 1 mL of Restylane-L in the nasolabial folds.
  • Photo of a 46-year-old patient treated with 2 mL of Restylane Silk in the lips and perioral lines and 2 mL of Restylane-L in the nasolabial folds.

Questions & Answers


Restylane® Silk is a transparent hyaluronic acid gel that is injected into patients’ lips and wrinkles around the mouth. Hyaluronic acid is a protective and lubricating gel that is produced naturally by the body. Restylane Silk is a new approved material that may increase the volume of patients’ lips and may smooth wrinkles around the mouth.


Like other areas of the face, the lips and skin surrounding the mouth show signs of aging as an individual gets older. This often results in lip thinning, lost shape and an increase in vertical lines above the lip.

Restylane Silk is designed specifically to provide natural-looking results in these areas. That’s why it’s made of smaller, smoother particles than those used in other Restylane products.

In a clinical study of patients treated with Restylane Silk or no treatment, clinical investigators reported:

77% of patients treated with Restylane Silk showed at least a one-point improvement in lip fullness (measured on on a 5-point scale) eight weeks after treatment.
59% of patients treated with Restylane Silk maintained lip fullness six months after treatment
Restylane® Silk’s unique particle gel formula, along with an ultrafine needle designed for improved accuracy, helps give you softer, more precise results — just what you need for a natural-looking smile.

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